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Essentials in Modern HPLC Separations de Serban C. Moldoveanu

Essentials in Modern HPLC Separations

Autor Serban C. Moldoveanu, Victor David
en Limba Engleză Paperback – 28 iun 2022
Essentials in Modern HPLC Separations, Second Edition discusses the role of separation in high performance liquid chromatography (HPLC). This new and updated edition systematically presents basic concepts as well as new developments in HPLC. Starting with a description of basic concepts, it provides important guidance for the practical utilization of various HPLC procedures, such as the selection of the HPLC type, proper choice of the chromatographic column, selection of mobile phase and selection of the method of detection, all of which are in correlation with the physico-chemical characteristics of the compounds separated.
Every chapter has been carefully reviewed, with several new sections added to bring the book completely up-to-date. Hence, it is a valuable reference for students and professors in chemistry.


  • Provides a thoroughly updated resource, with an entirely new section on Computer-aided Method Development in HPLC and new subsections on miniaturization and automation in HPLC, chemometric aspects of HPLC, green solvent use in HPLC, and more
  • Includes insights into the chromatographic process to find the optimum solution for analyzing complex samples
  • Presents a basis for understanding the utilization of modern HPLC for applications, particularly for the analysis of pharmaceutical, biological, food, beverage and environmental samples
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Specificații

ISBN-13: 9780323911771
ISBN-10: 0323911773
Pagini: 716
Dimensiuni: 191 x 235 mm
Greutate: 1.21 kg
Ediția:2
Editura: ELSEVIER SCIENCE

Cuprins

Part 1. Basic information about HPLC1. Introductory information regarding HPLC 2. Overview of HPLC instrumentation and its use3. Parameters for the characterization of HPLC separation4. Equilibrium types in HPLC5. Intermolecular forces6. Characterization of analytes and matrices 7. Mobile phases and their properties8. Analytical HPLC columns and their characteristics
Part 2. Main types of HPLC separations 9. Reversed-phase HPLC10. Other HPLC separations performed on hydrophobic stationary phases11. Hydrophilic interaction chromatography (HILIC)12. Other HPLC separations performed on polar stationary phases13. Ion-exchange, ion-moderated, and ligand-exchange liquid chromatography14. Chiral HPLC Separations15. Size exclusion HPLC16. Affinity, immunoaffinity, and aptamer type HPLC17. Mixed mode HPLC
Part 3. Practice of HPLC analysis18. Utilization of HPLC in chemical analysis
Part 4. Appendices

Notă biografică

Dr. Serban C. Moldoveanu held several teaching positions at the University of Bucharest, Romania, until 1983, when he immigrated to the United States. There, he continued teaching at the university level for several years before focusing primarily on industrial research. He served as Senior Principal Scientist at R.J. Reynolds Tobacco Company and retired at the end of 2023. His research has centered on various aspects of chromatography, including method development for the analysis of natural products using GC/MS, HPLC, and LC/MS/MS. He has also investigated the pyrolysis of a variety of polymers and organic compounds. Dr. Moldoveanu has published more than 150 articles in peer-reviewed journals, 8 books with Elsevier, approximately 22 patents/patent applications, and several book chapters. He was honored with the Tobacco Science Research Conference Lifetime Achievement Award in 2012 and currently serves as an editor for three chemistry journals.