This book deals with the field of hypertension study. The book offers a broad overview comprising the intricate aspects of the subject. It details the modern developments in genetics and pathophysiology of hypertension, specially the genetic determinants of hypertension and function of gene variants in response to anti-hypertensive treatment. It thoroughly analyzes mitochondrial alterations in vital hypertension and left ventricular hypertrophy. The book explains the universal gene appearance in hypertension. Furthermore, it presents the latest research on pathophysiology of defiant hypertension. Several other topics such as treating organ injuries and the purpose of music therapy in essential hypertension are explained in this book.