Endophthalmitis refers to the inflammation of the intraocular tissues and fluids of the eye and can be non-infectious or caused by bacterial, fungal or parasitic infection. It can be classified as exogenous (post-operative, post-traumatic or as a complication of a corneal ulcer) or endogenous (secondary to hematogenous spread from another infected site). This book discusses the clinical manifestations, relevance of diagnosis, and involved species of fungal endophthalmitis. It also examines anti-vascular endothelial growth factor medications; prevention and treatment of postoperative endophthalmitis; and a pharmacokinetic review of antibiotics used in the treatment of endophthalmitis.