Scott, a veteran disease investigator takes the newbe Sara under his wing and teaches her all that he knows about the taboo world of STD investigations. Their adventure begins with a simple gonorrhea case but soon they find a greater threat. The investigators must manage a multitude of unusual behaviors and personal conflicts to identify the source. The trail leads through a strange world hidden in plane view. Each encounter is an opportunity to teach, learn, and stop the spread of disease before it's too late.