The book presents an elaborative analysis of deep vein thrombosis providing information regarding the risk factors for DVT, vena cava malformation as a novel etiological factor and thrombosis in the upper limbs, post thrombotic syndrome and its management. DVT is usually observed in patients going through major surgeries. This book also extensively elaborates guidelines for thrombo-prophylaxis in orthopaedic patients, laparoscopic operations, radical pelvic surgeries and risks versus benefits in regions where DVT is less prevalent along with an overview of endovascular therapies and imaging in acute DVT, the various challenges in developing countries, and hypercoagulability in liver diseases. Cancer and its treatment are considered as risk factors for VTE and prolonged prophylaxis in ambulatory cancer patients is discussed.