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Cyclic Peptides: Methods in Enzymology, cartea 723

David Christianson Parisa Hosseinzadeh
en Limba Engleză Hardback – 19 noi 2025
Cyclic Peptides, Volume 721 covers peptide structures and their enhancement, stability, specificity, and overall functionality. As a growing suite of computational and experimental tools support the discovery and optimization of these molecules, ranging from well-established modeling platforms to emerging deep-learning algorithms that expand design possibilities, this book aims to provide a comprehensive overview of cyclic peptide research, covering fundamental principles, production strategies, and the latest technological advances in both synthetic and computational realms.

Cyclic peptides are a powerful approach to constraining peptide structures, enhancing their stability, specificity, and overall functionality. They can be generated through diverse techniques—including chemical synthesis, mRNA display, and DNA display—that enable the creation of tailored peptide libraries.

  • Spans a wide spectrum of cyclic peptide research, ensuring a comprehensive perspective that covers everything from foundational concepts to cutting-edge applications
  • Features insights from principal investigators at different career stages, offering diverse viewpoints and mentorship strategies
  • Embraces a breadth of topics—from purely computational approaches and display technologies to practical binder design—providing a holistic view of the field
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Specificații

ISBN-13: 9780443429514
ISBN-10: 0443429510
Pagini: 534
Dimensiuni: 152 x 229 mm
Greutate: 0.45 kg
Editura: ELSEVIER SCIENCE
Seria Methods in Enzymology


Cuprins

1. To be determined
Yu-Shan Lin
2. Using NMR Spectroscopy to Study the Folding and Supramolecular Assembly of Conformationally Constrained β-Sheet Peptides
James S. Nowick and Jason Zhu
3. To be determined
Ali Tavassoli
4. Using AEP enzymes to cyclize cyclotides: ultrastable constrained peptides
David J. Craik
5. Translational synthesis of constrained cyclic peptides using genetic code reprogramming”
Toby Passioura
6. To be determined
Parisa Hosseinzadeh and Paris Watson
7. To be determined
Parisa Hosseinzadeh, Noora Azadvari and Ben Burress-Irving
8. To be determined
Ben Brown
9. To be determined
Scott Lokey
10. Cyclic peptides as ligands for competition binding assays
James Inglese
11. To be determined
Alvaro Siano
12. To be determined
Gaurav Bhardwaj
13. To be determined
Vikram Khipple Mulligan
14. To be determined
Eugene Serebryany