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Continuous Biopharmaceutical Processes

Autor David Pfister, Lucrèce Nicoud, Massimo Morbidelli
en Limba Engleză Hardback – 11 oct 2018
This innovative reference provides a coherent and critical view on the potential benefits of a transition from batch to continuous processes in the biopharmaceutical industry, with the main focus on chromatography. It also covers the key topics of protein stability and protein conjugation, addressing the chemical reaction and purification aspects together with their integration. This book offers a fine balance between theoretical modelling and illustrative case studies, between fundamental concepts and applied examples from the academic and industrial literature. Scientists interested in the design of biopharmaceutical processes will find useful practical methodologies, in particular for single-column and multi-column chromatographic processes.
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Specificații

ISBN-13: 9781108420228
ISBN-10: 1108420222
Pagini: 348
Ilustrații: 142 b/w illus. 11 colour illus. 29 tables
Dimensiuni: 175 x 250 x 23 mm
Greutate: 0.78 kg
Editura: Cambridge University Press
Locul publicării:Cambridge, United Kingdom

Cuprins

Preface; 1. Introduction to biopharmaceutical processes; 2. Fundamentals of protein chromatography; 3. Counter-current separation processes; 4. Counter-current chromatography for the capture step; 5. Counter-current chromatography for the polishing steps; 6. Protein conjugation; 7. Protein aggregation in biopharmaceutical processes; 8. Conclusion; References; Notation; Index.

Descriere

Provides a coherent and critical view on the potential benefits of various continuous processes in the biopharmaceutical industry.