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Computational Non-coding RNA Biology

Autor Yun Zheng
en Limba Engleză Paperback – 19 sep 2018
Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different classes of non-coding RNAs and predicting the possible functions of these molecules.
Finding, quantifying, and visualizing non-coding RNAs from high throughput sequencing datasets at high volume is complex. Therefore, it is usually possible for biologists to complete all of the necessary steps for analysis.


  • Presents a comprehensive resource of computational methods for the identification and quantification of non-coding RNAs
  • Introduces 23 practical computational pipelines for various topics of non-coding RNAs
  • Provides a guide to assist biologists and other researchers dealing with complex datasets
  • Introduces basic computational methods and provides guidelines for their replication by researchers
  • Offers a solution to researchers approaching large and complex sequencing datasets
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Specificații

ISBN-13: 9780128143650
ISBN-10: 0128143657
Pagini: 320
Dimensiuni: 191 x 235 x 20 mm
Editura: ELSEVIER SCIENCE

Public țintă

Biologists, computational biologists, researchers in proteins and proteomics, botanists; researchers and graduate researchers working on non-coding RNA data.

Cuprins

PART 1 - BACKGROUND
1. Introductions
PART 2 - SMALL NCRNAS
2. Identification of microRNAs
3. Identification of TAS and PHAS
4. Identification of editing and mutation sites in miRNAs
PART 3 - MIRNA TARGETS
5. Identifying animal miRNA targets
6. Identifying plant miRNA targets
PART 4 - LONG NCRNAS 
7. Identification of long non-coding RNAs
8. Identification of lariat RNAs
9. Identification of circular RNAs
A. A usage guide of web-based ncRNA resources
B. Abbreviations and acronyms