This book is the result of a careful selection of contributors in the field of CFD. It is divided into three sections according to the purpose and approaches used in the development of the contributions. The first section describes the "high-performance computing" (HPC) tools and their impact on CFD modeling. The second section is dedicated to "CFD models for local and large-scale industrial phenomena." Two types of approaches are basically contained here: one concerns the adaptation from global to local scale, - e.g., the applications of CFD to study the climate changes and the adaptations to local scale. The second approach, very challenging, is the multiscale analysis. The third section is devoted to "CFD in numerical modeling approach for experimental cases." Its chapters emphasize on the numerical approach of the mathematical models associated to few experimental (industrial) cases. Here, the impact and the importance of the mathematical modeling in CFD are focused on. It is expected that the collection of these chapters will enrich the state of the art in the CFD domain and its applications in a lot of fields. This collection proves that CFD is a highly interdisciplinary research area, which lies at the interface of physics, engineering, applied mathematics, and computer science.