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Comprehensive Medicinal Chemistry III

Samuel Chackalamannil, David Rotella, Simon Ward
Notă GoodReads:
en Limba Engleză Carte Hardback – 15 Jun 2017
Comprehensive Medicinal Chemistry III provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery.


  • Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry
  • Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets
  • Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs
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Specificații

ISBN-13: 9780128032008
ISBN-10: 0128032006
Pagini: 4536
Dimensiuni: 216 x 276 mm
Greutate: 3.29 kg
Ediția: 3
Editura: ELSEVIER SCIENCE

Cuprins

Volume 1: General Perspective - The Future of Drug Discovery
Volume 2: Drug Discovery Technologies
Volume 3: In Silico Drug Discovery Tools
Volume 4: Experimental ADME and Toxicology
Volume 5: Cancer, Immunology and Inflammation, and Infectious Disease
Volume 6: CNS, Pain, Metabolic Syndrome, Urology, Gastrointestinal and Cardiovascular
Volume 7: Biologics Medicine
Volume 8: Case Histories in Recent Drug Discovery