The Newtonian mindset has dominated the entire human world for more than three centuries. It has provided the necessary knowledge, theories and conceptual foundation that supported the industrial revolution, hierarchical leadership and governance, deliberate planning and strategy, and operational control of all organizations. However, over the last few decades, constraints and incoherency are emerging due to new accelerants and elevating complexity density. The new situation and dynamics, and the multi-dimensional changes require a fresh thinking and deeper comprehension that is beyond the boundaries of the exact sciences. As the continuality of human existence requires a new global order to be established, a paradigmatic shift is essential. This book provides the foundation for nurturing the new intelligence mindset that is critical in the present context. Fundamentally, the intelligence mindset encompasses intelligence/consciousness-centricity, complexity-centricity, network-centricity and stability-centricity, and constructionist thinking as its foundation pillars. The conceptual foundation of this new paradigmatic shift is presented as the intelligent organization theory, and the theory of relativistic complexity. The intelligent organization theory (encompassing iCAS, iCAD, self-centricity, stability-centricity, organizing around intelligence, localized order, ..., mental cohesion) also provides a conceptual foundation to certain thinking and dynamics associated with Brexit and the current US under President Donald Trump.