Classics in Total Synthesis IV

K. C. Nicolaou is the Harry C. and Olga K. Wiess Chair in Natural Sciences at Rice University (Houston, USA). The impact of his work in chemistry, biology, and medicine flows from his contributions to chemical synthesis as described in over 800 publications. He is the recipient of numerous Prizes, Awards and Honors and has been elected to several Academies.

Ruocheng Yu is a postdoctoral fellow in the laboratory of Emily Balskus at Harvard University (Cambridge, USA). He pursued his doctoral studies under the guidance of K. C. Nicolaou at The Scripps Research Institute (La Jolla, USA), and later Rice University (Houston, USA).

Stephan Rigol joined the group of K. C. Nicolaou at Rice University (Houston, USA) after completing his doctorate at Leipzig University (Germany). He is currently conducting research in the field of natural products chemistry with a particular focus on molecules with antibacterial and anti-cancer activities.

1. Introduction: Total Synthesis Marching on with New Methods and Strategies and with Molecules for Biology and Medicine
2. Halichondrin B and Norhalichondrin B
3. Daphmanidin E
4. Epicoccin G and (-)-Acetylaranotin
5. Taiwaniadducts B, C, and D
6. Schindilactone A
7. Welwitindolinones
8. Ryanodine and Ryanodol
9. Gedunin, Mitrephorone A, and Antiretroviral Agent Islatravir
10. Trioxacarcins
11. Aplyviolene
12. Dixiamycin B
13. Ingenol
14. Cardamom Peroxide, Nodulisporic Acid C, and Bilobalide
15. Batrachotoxin and Conidiogenones
16. Gukulenin B and C-H Functionalization