Isabelle Van Helsing comes from a long and proud lineage, descended from the same man that went face-to-face with Dracula himself. Now that the world knows the supernatural exists, she is tasked with arresting and exterminating them, working for a government entity called The Initiative. And there are shadows lurking just waiting for the opportune moment to take it all down. After the death of a fellow Exterminator, Izzy and her snarky cohort and boyfriend Jonas McGrady, go to work investigating her death, finding that things aren't as black and white as they seemed.