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Cell Biology de Thomas D. Pollard

Cell Biology

Autor Thomas D. Pollard, William C. Earnshaw, Jennifer Lippincott-Schwartz, Graham Johnson
en Limba Engleză Hardback – 28 feb 2023
Reader-friendly Cell Biology, 4th Edition, provides a concise but comprehensive foundation for students entering research or health care career paths. Award winning illustrations help readers quickly grasp general principles. The authors have thoroughly updated this popular text to provide readers with the current understanding of the principles of normal cellular function along with examples of how molecular defects predispose to human disease. Major new themes in the 4th edition include the roles of intrinsically disordered polypeptides and phase separation in cellular functions, the influence of new molecular structures on understanding mechanisms, and the impact of exciting new methods-from single cell RNA sequencing to second generation super resolution fluorescence microscopy-on advancing our understanding.
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Specificații

ISBN-13: 9780323758000
ISBN-10: 0323758002
Pagini: 944
Dimensiuni: 216 x 276 x 34 mm
Greutate: 2.09 kg
Ediția:4
Editura: Elsevier

Cuprins

SECTION I Introduction to Cell Biology
1. Cells as the Basis of Life on Earth
2. Evolution of Life on Earth

SECTION II Chemical and Physical Background
3. Molecules: Structures and Dynamics
4. Biophysical Principles
5. Macromolecular Assembly
6. Research Strategies

SECTION III Chromatin, Chromosomes, and the Cell Nucleus
7. Chromosome Organization
8. DNA Packaging in Chromatin and Chromosomes
9. Nuclear Structure and Dynamics

SECTION IV Central Dogma: From Gene to Protein
10. Gene Expression
11. Eukaryotic RNA Processing
12. Protein Synthesis and Folding

SECTION V Membrane Structure and Function
13. Membrane Structure and Dynamics
14. Membrane Pumps
15. Membrane Carriers
16. Membrane Channels
17. Membrane Physiology

SECTION VI Cellular Organelles and Membrane Trafficking
18. Posttranslational Targeting of Proteins
19. Mitochondria, Chloroplasts, Peroxisomes
20. Endoplasmic Reticulum
21. Mechanisms of Vesicular Transport
22. Secretory Membrane System and Golgi Apparatus
23. Endocytosis and the Endosomal Membrane System
24. Processing and Degradation of Cellular Components

SECTION VII Signaling Mechanisms
25. Plasma Membrane Receptors
26. Protein Hardware for Signaling
27. Second Messengers
28. Integration of Signals

SECTION VIII Cellular Adhesion and the Extracellular Matrix
29. Cells of the Extracellular Matrix and Immune Systems of Animals
30. Extracellular Matrix Molecules
31. Cellular Adhesion
32. Intercellular Junctions
33. Connective Tissues

SECTION IX Cytoskeleton and Cellular Motility
34. Actin and Actin-Binding Proteins
35. Microtubules and Centrosomes
36. Intermediate Filaments
37. Motor Proteins
38. Intracellular Motility
39. Cellular Motility
40. Muscles

SECTION X Cell Cycle
41. Introduction to the Cell Cycle
42. G1 Phase and Regulation of Cell Proliferation,
43. S Phase and DNA Replication
44. G2 Phase: Responses to DNA Damage and Control of Entry Into Mitosis
45. Mitosis
46. Cytokinesis
47. Meiosis
48. Cell Death