Calcific aortic valve disease (CAVD) has become the most widespread cardiac valve disease in the economically advanced nations. Population ageing is one of the major reasons for this increasing rate. There is no definite treatment which may slow down the disease progression; valve replacement is the only adequate treatment. This book encompasses the understandable fundamental biology of cardiac valve and procedures of CAVD. It also discusses genetics, proteomics and metabolism of CAVD, depicts novel methods in valve tissue engineering and regenerative medicines. This book will facilitate people to know about CAVD and other aspects concerning valve biology. It also emphasizes on the prospective chances of curbing the disease from rising in future.