Breast Epithelial Antigens de R. L. Ceriani

Breast Epithelial Antigens

R. L. Ceriani

Reporting on the clinical procedures that have now been developed from the initial research on using monoclonal antibodies to diagnose and treat breast cancer, the 21 papers also review promising research still in the pipeline. The various descriptions of breast epithelial antigens consider their mo

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Cuprins

Session I.- Molecular Analysis of H23 Epithelial Tumor Antigen - Differentially Spliced Full Length cDNAs and Gene.- Characterization and Evolution of an Expressed Hypervariable Gene for Tumor-Associated Mucin, MUC-1.- Structure, Processing, Differential Glycosylation and Biology of Episialin.- Molecular Cloning and Expression of Breast Mucin-Associated Antigens.- Monoclonal Antibodies Reactive with Breast Cancer, Mammary Mucins and Synthetic Peptides.- Molecular Analysis of Epitopic Heterogeneity of the Breast Mucin.- Session II.- Expression and Prognostic Significance of the Her-2/NEU Oncogene During the Evolutionary Progression of Human Breast Cancer.- Structure and Function of MFG-E8: A Novel Apical Membrane Protein of Mouse Mammary Ephelial Cells.- Targeted Lysis of Human Breast Cancer Cells by Human Effector Cells Armed with Bispecific Antibody 2B1 (ANTI-c-erbB-2/ANTI-Fcy Receptor III).- Mechanisms Controlling Steroid Receptor Binding to Specific DNA Sequences.- Session III.- Origin and Nature of the Milk Lipid Globule Membrane.- N-Linked Oligosaccharide Synthesis and Cellular Sociology.- Development of Enzyme Immunoassays for Breast Carcinoma-Associated Mucin Antigens.- Clinical Studies and New Developments with Hybri-BREScan (CA-549), A Monoclonal Assay for Breast Cancer-Associated Antigen.- Evaluation of Several Tumor Markers (MCA, CA 15.3, BCM and CA 549) in Tissue and Serum of Patients with Breast Cancer.- IMx BCM: A Novel Monoclonal Based System for the Detection of Breast Cancer Associated Mucin.- A Novel Serum Assay Using Recombinant Breast Epithelial Mucin Antigen.- Session IV.- RadioimmunoguidedTM Surgery in Breast Cancer.- Immuno-Pharmacologic Purging of Breast Cancer from Bone Marrow.- Imaging, Pharmacokinetics, Dosimetry and Antitumor Effects of Radiolabeled Anti-Breast Cancer Antibodies in Mouse and Man.- Radioimmunotherapy with I-131 Chimeric L-6 in Advanced Breast Cancer.- Contributors.