Bone tumours are very rare, accounting for less than 0.2% of all cancers. As our understanding of these tumours at the molecular level is improving, as well as recent advances in imaging and treatments, there is an obvious need for an update in this field. This comprehensive book is the result of the contribution of different internationally renowned expert teams in the management of bone tumours and particularly spinal neoplasms. The first five chapters deal with spinal tumours, either primary or metastatic, giving the reader a clear clinical review of the disease and its pathophysiology, as well as therapeutic options. The following chapters are dedicated to new insights in the medical treatment of bone tumours, an overview on the mechanism of malignant transformation of benign bone tumours, the modern management of pain in bone metastases, and the modern therapeutics of bone tumours in prostate cancer patients.