The vaccine continues to spread. Humans flock to get the serum, not realizing the control they are giving up. Isabella Howerton has reunited with her brother, but the world as she knew it has changed. While her brother works to counter the vaccine he helped create, Isabella struggles with her role in the new world. Protecting those she cares about has always been her number one priority, but what can a frail human do against vampires and werewolves? She can either be a pawn, or learn to fight. Each decision Isabella makes will have consequences, some of which may be deadly.