Biochemistry, An Integrative Approach with Expanded Topics, offers a unique approach to the subject, emphasizing problem-solving and critical thinking over rote memorization. It integrates subjects of interest to undergraduates majoring in, biochemistry, life science, and beyond while preserving a chemical perspective. The book covers DNA, RNA, gene regulation, synthetic proteins, omics, plant biochemistry, and more. Key concepts such as metabolism, are introduced and then revisited and cross-referenced throughout the text to establish pattern recognition and help students commit their new knowledge to long-term memory. Emphasis is also laid on problem-solving and reasoning skills essential to life sciences, including data analysis and research assessment. This edition of the book aims to empower students studying a range of disciplines to develop a lasting foundation in biochemistry and metabolism.