Cantitate/Preț
Produs
Total produse
Vezi coșul
Biochemistry: Essential Concepts de Charles Hardin

Biochemistry: Essential Concepts

Autor Charles Hardin, James Knopp
en Limba Engleză Paperback – 12 iun 2026
One-semester biochemistry courses are notorious for overwhelming students with the magnitude of material covered in their texts and lectures. Biochemistry: Essential Concepts distills the basic ideas covered in a one-semester course without the extraneous details that burden most texts.Authors Charles Hardin and James Knopp demonstrate the core concepts of biochemistry - including cell biology, amino acids, metabolism, and DNA - in a variety of real-world contexts. With the last forty percent of the text devoted to review questions and practice tests, Biochemistry: Essential Concepts equips students for success in the one-semester biochemistry course and prepares them for their future studies and careers.
Citește tot Restrânge

Preț: 61853 lei

Preț vechi: 80328 lei
-23% Nou

Puncte Express: 928

Carte disponibilă

Livrare economică 28 septembrie-12 octombrie

Livrare prin curier în România Termenul estimat este afișat lângă disponibilitate.
Transport gratuit pentru acest produs Plată online sau ramburs, în funcție de opțiunile comenzii.
Retur gratuit în 14 zile Comandă securizată și suport în română.
 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă

Specificații

ISBN-13: 9780199765621
ISBN-10: 0199765626
Pagini: 336
Dimensiuni: 277 x 213 x 15 mm
Greutate: 0.84 kg
Editura: Oxford University Press
Colecția OUP USA
Locul publicării:New York, United States

Notă biografică

Hardin, Charles C., Associate Professor, North Carolina State University (Ph.D. in Biochemistry, Spectroscopy, computational chemistry from Iowa State University)Knopp, James A., Associate Professor, North Carolina State University (Ph.D. in Biophysical Chemistry from University of Illinois at Urbana)

Cuprins

  • Brief Contents
  • Preface
  • Acknowledgement
  • Chapter 1. Biochemistry: Subject Overview
  • 1.1 Central Themes
  • 1.2 Central Dogma of Molecular Biology
  • Chapter 2. Cell Biology Review
  • 2.1 The Animal Cell
  • 2.2 The Plant Cell
  • 2.3 Selected Organelles
  • 2.4 The Cell Cycle: Mitotic Cell Division
  • 2.5 Viruses
  • Chapter 3. Chemistry Review
  • 3.1 Organic Compounds
  • 3.2 Chirality
  • 3.3 Chemical Reactions
  • 3.4 Physical Chemistry Concepts
  • 3.5 Buffering of Blood: The Bicarbonate System
  • Chapter 4. Amino Acids
  • 4.1 Basic Structures
  • 4.2 Amino acid 'R Groups'
  • 4.3 Ionization Properties
  • 4.4 Drawing Peptide Titration Plots
  • 4.5 Factors That Influence the pKa of Protonatable/Deprotonatable Groups in Proteins
  • Chapter 5. Proteins
  • 5.1 Peptide Bonds
  • 5.2 Purification and Characterization of Proteins
  • Chapter 6. Protein Structure
  • 6.1 Conformation
  • 6.2 Classification of Substructure
  • 6.3 Alpha (?) Helices
  • 6.4 Beta Sheets
  • 6.5 U-Turns
  • 6.6 Ramachandran Plot
  • 6.7 Stabilizing Factors
  • 6.8 Thermodynamics of Protein Folding: The Hydrophobic Effect
  • 6.8.1 Temperature-Dependant Denaturation
  • 6.9 Chaotropes and The Hofmeister Series
  • 6.10 Sodium Dodecyl Sulfate (SDS): Chaotrope Action
  • 6.11 Visualizing the Energy Landscape
  • 6.12 Protein Maturation
  • Chapter 7. Ligand Binding and Functional Control
  • 7.1 Oxygen Transport in Blood
  • 7.2 Hemoglobin Oxygen Binding: Cooperativity
  • 7.3 Antibodies: Immunological Recognition
  • Chapter 8. Enzymes
  • 8.1 Enzymes are Biological Catalysts
  • 8.2 Enzyme Function: Activity Assays and Enzyme Kinetics
  • 8.3 Requirements for Catalysis
  • 8.4 Comparing Enzymes and Relative Efficiency of Use of Substrates
  • 8.5 Drug Design
  • 8.6 Enzyme Inhibitors
  • 8.7 Allosterism
  • 8.8 Phosphorylation and Dephosphorylation
  • Chapter 9. Metabolic Enzyme Action
  • 9.1 Enzyme Mechanisms
  • 9.2 Modes of Catalysis
  • 9.3 The Reaction Coordinate
  • 9.4 Induced Fit Revisited
  • 9.5 Acid-Base Catalysis
  • 9.6 Covalent Group Transfer
  • 9.7 The Serine Protease Catalytic Triad Mechanism
  • 9.8 The Active Site of Tyrosyl-tRNA Synthetase
  • Chapter 10. Coenzymes
  • 10.1 Classification
  • 10.2 Survey of the Coenzymes
  • 10. 3 Metals
  • 10.4. Carbohydrates-Based Cofactors
  • 10.5 Fat Soluble Vitamins
  • Chapter 11. Carbohydrates and Glycoconjugates
  • 11.1 Carbohydrates: Definition
  • 11.2 Monosaccharides: Aldoses
  • 11.3 Monosaccharides: Ketoses
  • 11.4 Structural Features
  • 11.5 Intramolecular Cyclization
  • 11.6 Conformations: Sugar Puckers
  • 11.7 Sugar Derivatives
  • 11.8 Disaccharides
  • 11.9 Polysaccharides
  • 11.10 Carbohydrate-Protein Conjugates
  • 11.11 Synthesis and Structural Characterization
  • Chapter 12. Lipids
  • 12.1 Structural Overview
  • 12.2 Saturated and Unsaturated Fatty Acids
  • 12.3 Functions
  • 12.4 Diacylglycerol Lipid Derivatives
  • 12.5 Structural Motifs
  • 12.6 Assembly
  • 12.7 Structural and Dynamic Characterization
  • 12.8 Eicosanoids
  • 12.9 Phospholipases
  • 12.10 Phosphoinositides
  • 12.11 Steroids
  • 12.12 A Potpourrié of Lipids
  • Chapter 13. Membranes
  • 13.1 The Fluid Mosaic Model
  • 13.2 Detergents
  • 13.3 Distribution of Lipids in Biological Membranes
  • 13.4 The Hydropathicity Scale
  • 13.5 Lipid-Anchored Membrane Proteins
  • 13.6 The Erythrocyte Cytoskeleton
  • Chapter 14. Transport Through Membranes
  • 14.1 The Transmembrane Potential
  • 14.2 Active Transport
  • 14.3 Ionophores
  • 14.4 The Acetylcholine Receptor Ion Channel
  • 14.5 Lactose Permease and Secondary Active Transport
  • 14.6 Mechanism of Transport by Na+, K+ ATPase
  • 14.7 Ion Channel Blockers
  • Chapter 15. Signal Transduction
  • 15.1 Signaling Pathways: Hormones, GTPases, Second Messengers and Intracellular Regulation .. 120
  • 15.2 The Adenylate Cyclase Signaling Pathway
  • 15.3 The Inositol-Phospholipid Signaling Pathway
  • 15.4 Phorbol Myristyl Acetate
  • 15.5 The Insulin Receptor
  • 15.6 Glucagon
  • 15.7 G-Proteins
  • Chapter 16. Nucleic Acids: DNA
  • 16.1 DNA and RNA
  • 16.2 Physical Properties
  • 16.3 Secondary Structure
  • 16.4 Backbone Structure
  • 16.5 Counterions
  • 16.6 Chemical Synthesis
  • 16.7 Watson-Crick Base Pairs
  • 16.8 Structural Modifications
  • 16.9 Three-Dimensional Structures
  • 16.10 Recognition of Sequences
  • 16.11 Genetic Mutations and Antisense Nucleic Acids
  • 16.12 Unusual DNA
  • 16.13 Stabilization of Nucleic Acids
  • 16.14 Secondary Structure Predictions
  • 16.15 Chromosomes
  • 16.16 Some Protein Nucleic Acid Binding Motifs
  • 16.17 Recombination
  • Chapter 17. RNA
  • 17.1 Cells Contain a Variety of Types of RNA
  • 17.2 RNAs Have Stable Secondary Structure
  • 17.3 Tertiary Structure: Transfer RNA
  • 17.4 Messenger RNA (mRNA)
  • 17.5 Eukaryotic Messenger RNA
  • 17.6 Alkaline Hydrolysis of RNA
  • 17.7 Small Interfering RNA
  • Chapter 18. Biotechnology
  • 18.1 Restriction Endonucleases
  • 18.2 Cloning in a Nutshell
  • 18.3 DNA Preparation: Phenol-Chloroform Extraction
  • 18.4 Polymerase Chain Reaction
  • 18.5 Probe DNA
  • Chapter 19. Metabolism
  • 19.1 Overview
  • 19.2 Metabolic Pathway Types
  • 19.3 Energy Conservation
  • 19.4 Key Pathways/Reactions
  • Chapter 20. Bioenergetics
  • 20.1 Reaction Equilibria: Standard and Actual Free Energies
  • 20.2 Metabolically Irreversible and Near Equilibrium Reactions
  • 20.3 Energies and Regulation of Glycolysis
  • Chapter 21. Bioelectrochemistry
  • 21.1 Redox Reaction Principles
  • 21.2 Redox Energetics: The Nernst Equation
  • 21.3 Electron Transport Chains
  • Chapter 22. Glycolysis
  • 22.1 Reactions 1 Through 10
  • 22.2 Regulation: Activation and Inhibition
  • 22.3 Four Fates of Pyruvate
  • Chapter 23. The Krebs Cycle
  • 23.1 Pathway
  • 23.2 Reactions
  • 23.3 Yields
  • 23.4 Cellular Redox Potential
  • 23.5 Regulation
  • Chapter 24. Gluconeogenesis
  • 24.1 Reactions
  • 24.2 Regulation
  • 24.3 Sources Used to Produce Glucose
  • Chapter 25. Electron Transport and Oxidative Phosphorylation
  • 25.1 Mitochondria in Red and White Muscle
  • 25.2 Overall Process
  • 25.3 Chemical and Potential Energies That Drive Proton Transport
  • 25.4 Mitochondrial Electron Transport
  • 25.5 Electron Transfer and Proton Flow in Complexes I through IV
  • 25.6 Oxidative Phosphorylation
  • Chapter 26. The Malate-Aspartate Shuttle and Proteomics
  • 26.1 Getting NADH Into the Mitochondrion: Isozymes
  • 26.2 Isozymes and Proteomics
  • 26.3 Characterization by Two-dimensional Gel Electrophoresis
  • 26.4 Mass Spectrometry and Proteomics
  • Chapter 27. Degradation and Synthesis of Lipids
  • 27.1 Beta Oxidation of Saturated Fatty Acids
  • 27.2 Biosynthesis of Fatty Acids
  • 27.3 Length Determination of Fatty Acids
  • 27.4 Synthesis of Acidic Phospholipids
  • 27.5 Cholesterol Biosynthesis
  • 27.6 Regulating Cholesterol Levels
  • Chapter 28. Photosynthesis
  • 28.1 Light and Dark Reactions
  • 28.2 Photo-Gathering Pigments
  • 28.3 Photosynthetic Electron Transport Pathway (Z scheme)
  • Chapter 29. The Calvin Cycle
  • 29.1 The Dark Reactions: Carbon Fixation
  • 29.2 Biosynthesis of Ribose-5-phosphate
  • 29.3 RuBisCO Mechanism
  • 29.4 The C4 and CAM Pathways
  • Chapter 30. The Urea Cycle
  • 30.1 Purpose and Reactions
  • 30.2 Regulation
  • 30.3 Comparative Nitrogen Excretion
  • 30.4 Protein Degradation and Programmed Cell Death
  • STUDY GUIDE
  • Review Session for Chapters 1 - 3
  • Review Session for Chapter 4
  • Review Session for Chapters 5 and 6
  • Review Session for Chapters 7 - 8.6
  • Review Sessions for Chapters 8.7 - 8.8
  • Review Session for Chapter 9
  • Review Session for Chapters 10 - 11.4
  • Review Session for Chapters 10 - 11.4: Key
  • Review Session for Chapters 11.5 - 12.5
  • Review Session for Chapters 11.5 - 12.5: Key
  • Review Session for Chapters 13 - 14.7
  • Review Session for Chapters 13 - 14.7: Key
  • Review Session for Chapters 16.2 - 17.6
  • Review Session for Chapters 16.2 - 17.6: Key
  • Review Session for Chapters 19 - 20
  • Review Session for Chapters 19 - 20: Key
  • Review Session for Chapters 21 - 25
  • Review Session for Chapters 21 - 25: Key
  • Review Session for Chapter 27
  • Review Session for Chapter 27: Key
  • Practice Exam 1, Key
  • Practice Exam 2, Key
  • Practice Exam 3, Key
  • Practice Exam 4, Key
  • Final Test Review
  • Final Test Review (with answers)