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Bioactive Compounds: Mechanisms, Challenges and Strategies for Bioaccessibility and Bioavailability

Editat de Cristobal Noe Aguilar, Eliseo Cárdenas Hernández, Rafael Matos Ximenes, Jose Sandoval Cortes
en Limba Engleză Paperback – mar 2027
Bioactive Compounds: Mechanisms, Challenges and Strategies for Bioaccessibility and Bioavailability brings together leading experts from the fields of nutrition, food science, and pharmacology to elucidate the intricate dynamics of bioactive compounds and their impact on human health. This comprehensive volume delineates the crucial differences between bioaccessibility and bioavailability, providing insight into their implications for health outcomes. Readers will explore the behavior of key classes of bioactive compounds, including polyphenols, carotenoids, and peptides, as well as their sources and interactions within the food matrix. The book further examines the essential role of gut microbiota in the absorption processes, highlighting how these interactions can influence bioactive compound efficacy in the human body. Bioactive Compounds: Mechanisms, Challenges and Strategies for Bioaccessibility and Bioavailability not only discusses the mechanisms of absorption, distribution, metabolism, and excretion (ADME) of bioactive compounds but also introduces cutting-edge tools and strategies designed to enhance their bioaccessibility and bioavailability. Chapters dedicated to innovative approaches, such as microfluidics and nanotechnology, provide practical insights into the development of effective delivery systems. With a focus on real-world applications and clinical implications, this book serves as a vital resource for academics, clinicians, food chemists, and nutritionists aiming to bridge the gap between research and application in the fields of nutraceuticals and functional foods while optimizing health outcomes.

  • Delineates the differences between bioaccessibility and bioavailability, along with their implications for health outcomes
  • Highlights the impact of the interaction of the main classes of bioactive compounds such as polyphenols, carotenoids, and peptides while addressing their sources, and behavior within the food matrix
  • Discusses the role of the gut microbiota in the absorption processes of bioactive compounds
  • Introduces tools and strategies to improve bioaccessibility and bioavailability, including microfluidics, and nanotechnology
  • Provides insights into bioactive compounds' bioaccessibility, bioavailability, health effects, absorption, and metabolism function
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Specificații

ISBN-13: 9780443442230
ISBN-10: 0443442231
Pagini: 375
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE

Cuprins

Section 1: Foundations of Bioactive Compounds
1. Introduction
2. Bioactive Compounds: Sources and Their Benefits to Human Health
3. Bioactive Compound Delivery Systems: Foods, Plant Matrices, Functional Foods, and Nutraceuticals
4. Bioaccessibility, Bioavailability and Bioactivity: Clarification of the Concepts, Key Challenges, and Future Directions

Section 2: Mechanisms of Absorption and Impact on Health
5. Process of Absorption, Distribution, Metabolism, and Excretion (ADME) of Bioactive Compounds
6. Impact of the Interaction of Bioactive Compounds within the Food Matrix on Their Bioaccessibility, Bioactivity, and Bioavailability
7. Role of the Gut Microbiota in the Absorption Processes of Bioactive Compounds
8. Human biochemistry of absorption and biotransformation of bioactive compounds: clinical trials and physiological applications
9. Influence of bioaccessibility and bioavailability on human health: role in the prevention and management of chronic diseases

Section 3: Factors Affecting Bioaccessibility and Bioavailability
10. Factors That Affect the Bioaccessibility and Bioavailability of Bioactive Compounds
11. Methods for the Determination of Bioaccessibility and Bioavailability of Bioactive Compounds: Traditional Approaches, Microfluidic and New Techniques
12. Strategies and Delivery Systems to Improve Bioaccessibility and Bioavailability of Bioactive Compounds: Limitations, Micro and Nanoencapsulation

Section 4: Innovative Approaches and Future Directions
13. In Vivo, In Vitro, or In Silico Tools for Predicting Pharmacokinetics of Bioactive Compounds
14. Can Informatics, Bioinformatics, and Artificial Intelligence Tools Help in the Study of Bioaccessibility and Bioavailability?
15. Innovative Product Development for Enhancing Bioaccessibility and Bioavailability of Bioactive Compounds: Practical Examples and Applications