When Brooke sets off on a trail in Yellowstone National Park to train for an upcoming marathon, she is savagely attacked by a grizzly bear. One hundred forty years earlier, Anne accompanies her husband on a camping trip in the nation's first national park and awakens one morning to find he's been captured by Nez Perce warriors. Both women encounter a sacred but savage landscape. Both fall under the care of American Indian women. Ultimately, Brooke and Anne must each overcome multiple obstacles, with the help of their new friends and native lore, to find what she seeks. Alternating between contemporary and historical times, Bear Medicine is a story about women helping women in a complicated, male-dominated world.