An authoritative treatise on the use, history, culture, and art of the sacred plant medicine Ayahuasca. Ayahuasca is the strongest shamanic plant medicine. Brewed from the combination of the Amazonian vine, Banisteriopsis caapi, and leaves from the plant, Psychotria viridis, Ayahuasca creates sweeping visual and mentally startling effects. For many of the indigenous cultures of the Amazonian basin, Ayahuasca is central to their culture, revealing to mankind its role in the universe and the true nature of reality. Used properly, Ayahuasca provides healing and integration with nature and community and stimulates the creative process. The authors are recognized experts in the field of ethnology, anthropology and pharmacology and demonstrate the use of Ayahuasca in shamanic rituals. They dive deep into shamanic visionary worlds, explore the plants and their souls, and share their authentic encounters with Amazonian cultures and their artistic works.