This proceedings volume contains selected chapters on topics related to artificial intelligence, cybersecurity and game design and their sustainable applications, emphasizing sustainable applications that directly address topics related to five SDGs areas (3, 6, 7, 9, 13). Chapters are based on invited talks and contributed papers presented at the International Conference on Artificial Intelligence, Cybersecurity and Game Design (ICAICGD 2024), held at Ramco Institute of Technology, Rajapalayam, Tamil Nadu, India, from 23–25 February 2024. The book offers a diverse array of new results, techniques, applications and perspectives: Out of 23 chapters, 4 chapters deal with security aspects, 2 on network science, 2 on game design, 4 on prediction models, 2 on recognition models, 3 on applications of AI tools such as machine learning and deep learning to agricultural science and 4 chapters are on applications to medical science.