Appendicitis remains one of the most common surgical emergencies, with approximately 200,000 annual cases in the United States and a lifetime risk of 8%. The treatment of appendicitis has evolved significantly, from the first reported appendectomy in 1736 at St. George's Hospital in London. This book discusses several topics on appendicitis including the surgical management of appendicitis; pediatric advanced appendicitis; acute appendicitis; treatment strategies; risk factors and clinical implications.