Depression is a common and debilitating condition, which affects approximately one in eight people. In addition, it is expected to be the second-leading cause of disability in the world by the year 2020. Nearly 10% of all primary care office visits are related to depression. Depression can be treated successfully and remission is associated with a return to a normal psycho social function and overall a better prognosis. I hope, that the 'Antidepressants Pocket Guide' will serve you as a useful guide for the treatment of your depressive patients.