The disease which is caused due to the accumulation of the protein amyloid in the organs is known as amyloidosis. Some of the prominent symptoms of this disease are fatigue and weakness, numbness in hands and feet, enlarged tongue, swelling around ankles, and shortness of breath. There are various subtypes of amyloidosis. A few of them are AL amyloidosis, AA amyloidosis, hereditary amyloidosis and localized amyloidosis. Complications of amyloidosis can affect the kidneys, heart and the nervous system. It can be diagnosed through imaging tests such as MRI, nuclear imaging and echocardiogram. The treatments of amyloidosis involves the management of symptoms using targeted therapies, chemotherapy and heart medications. This book outlines the diagnosis and treatment of amyloidosis in detail. The readers would gain knowledge that would broaden their perspective about this disease. This book will serve as a reference to a broad spectrum of readers.