Amphibian skin has, over the last century, proven to contain a treasure-trove of biologically active compounds. Since that time further investigation has added hundreds of such compounds to the list of active substances from amphibian skin. Peptides, proteins, bufadienolides steroids and alkaloids (tetrodotoxins, biogenic amines and lipophilic alkaloids) represent the main compounds found in the amphibian skin. This book discusses the anatomy of amphibians. It also provides topics on the ecological significant and conservation strategies of these marine animals.