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Aging de Sean P Curran

Aging

Editat de Sean P Curran
en Limba Engleză Hardback – 24 ian 2027

The biology of aging has emerged as one of the most dynamic and interdisciplinary areas of modern biomedical research. This second edition volume expands on the previous edition by bringing together established and emerging methodologies that enable investigators to study aging at molecular, cellular, organismal, and population levels. Written in the highly successfulMethods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Aging: Methods and Protocols, Second Edition aims to provide practical guidance and a valuable resource for researchers and experts seeking to advance the science of aging and promote healthy longevity.

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Specificații

ISBN-13: 9781071657027
ISBN-10: 107165702X
Ediția:2nd Second 2027 edition
Editura: Springer Us

Cuprins

Calculating Epigenetic Clocks from DNA Methylation Data to Index Accelerated Epigenetic Aging.- A Standardized Workflow for Single-Cell/Nuclei RNA-seq Analysis in Aging Research.- Isolation and Functional Screening of Plant¿Derived Natural Products for Assessing Healthy Aging and Neuroprotective Activities in Caenorhabditis elegans.- Translational Profiling of Adult C. elegans Glia using Translating Ribosome Affinity Purification (TRAP).- An Integrated Pipeline for Quantifying Survival, Cell Morphology, and Nuclear Integrity During Chronological Aging of Fission Yeast.- Practical Considerations for Automated Lifespan Measures in C. elegans.- Assessing Age-Related Changes in C. elegans Behavior Using the Forced Food Choice Assay.- Analyzing Spatial Learning Behavior and Cognitive Function in Aging Mice Using the Barnes Maze.- Quantification of C. elegans Movement and Muscle Function Using WormLab-Derived Maximum Dynamic Amplitude.- Voluntary Wheel Running as a Noninvasive and Low-Stress Exercise Paradigm in Aging Mice.- Characterizing Gut Diversity during Aging.- Massively Parallel, Ultra-Accurate RNA Sequencing with CircSeq.- RNAscope in the Brain of the Naturally Short-Lived African Turquoise Killifish.- Practical Guide to RNA Sequencing Analysis in Aging Research.- Mitochondrial-Wide Association Studies: Integrating Population-Based Data and Mitochondrial Genetics.- Imaging of Organelle and Actin Cytoskeletal Morphology During Aging.- Measurements of Nuclear Pore Function in Living Caenorhabditis elegans.-Measurement of Skeletal Muscle Mitochondrial DNA Synthesis Using Stable Isotope Labeling.- Mnemonic Similarity Task Variants for Probing Age-Related Memory Impairments Across Species and Modalities.- Guide to Extending Findings from Selected Samples Using Inverse Odds of Selection Weights.