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Aging and the Kidney: Mechanisms, Consequences, and Management Strategies

Editat de Stephen Fadem, Ahmed Arslan Yousuf Awan, Emaad Abdel-Rahman
en Limba Engleză Paperback – 27 iul 2026
Aging and the Kidney: Possible Mechanisms, Consequences, and Management Strategies explores the connection between kidney health and overall well-being with increasing age and longevity. The first part examines histological, structural, physiological, and functional changes that contribute to age-related declines in kidney function. The role of nutrition and proteomics is also discussed. The second part examines the functional decline in elderly patients and includes subparts on impaired quality of life, sleep quality, fall risk, frailty, depression, and sarcopenia. It also considers unique features of hypertension, diabetes, glomerulonephritis, and peripheral vascular disease.

The final part focuses on diagnostic, management, and prevention strategies. Common myths about chronic kidney disease in the elderly are addressed, with particular attention to how a solitary kidney in living donors ages over time. In addition, kidney function and its relationship to neurologic complications, cancers, and cardiovascular disease are explained, along with current treatment approaches, medications, and future directions in the care of elderly patients.

  • Covers histological, structural, physiological, and functional changes that lead to decline in kidney function with aging
  • Summarizes the most up-to-date research on the kidney’s impact on health and lifespan
  • Addresses common myths regarding kidney disease in the elderly
  • Provides guidance on diagnostic, management, and prevention strategies in kidney health and disease for the aging patient
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Specificații

ISBN-13: 9780443340697
ISBN-10: 0443340692
Pagini: 588
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE

Cuprins

Part 1: Mechanisms of aging in the kidney
1. Structural and functional changes in aging
2. Models of kidney aging
3. Molecular mechanisms of aging
4. A review of podocyte senescence and aging
5. Epigenetics and the kidney
6. The influence of acute kidney injury on aging
7. Nutritional considerations and aging
8. Proteomics
Part 2: Unique characteristics of kidney diseases in the elderly
9. Impaired quality of life in elderly CKD patients
10. Sleep
11. Falls
12. Fatigue and frailty in kidney disease
13. Hospitalizations
14. Depression
15. Sarcopenia
Part 3: Aging in specific diseases
16. Hypertension
17. Diabetes in kidney disease progression
18. Glomerulonephritis
19. Peripheral vascular disease
Part 4: Management and prevention
20. Diagnosis of CKD in an elderly individual, due to a decline in GFR with normal healthy aging
21. Myths about chronic kidney disease in the elderly
22. The living donor and aging
23. CNS limitations in elderly kidney patients
24. Cancer and the kidney in an elderly individual
25. Cardiovascular disease in aging kidney
26. Benefits of renin angiotensin aldosterone system blockage
27. Active medical care without dialysis
28. Drugs to avoid with geriatric kidney disease
29. Innovations in chronic kidney disease and aging