Stroke is a leading cause of mortality and morbidity worldwide. Just a decade ago, stroke management was simple. Apart from secondary prevention, and education, there was not much a clinician could do that would significantly change outcomes. There were no acute interventions, no tPA, and no endovascular therapies. Stroke was thus not an emergency. Today, we live in a different world. With the advent of tPA and endovascular intervention, acute stroke is an emergency of epic proportions. Time literally is brain and the clinician has to be acutely aware of the advances in stroke in order to maximize the therapeutic impact. Many books have been written about stroke. The authors and editors envisioned a succinct, yet comprehensive guide for the clinician in the management of stroke. From the medical management of stroke, to neuroimaging, thrombolysis, endovascular therapies, and rehabilitation, this book guides the novice clinician as well as the seasoned vascular neurologist to be able to recognize, manage, and treat acute stroke to the best of medical science's guidelines.