The ability to consistently make one's best possible decisions can be a major factor in achieving success in life. A systematic process for accomplishing this goal, along with relevant examples are described. In addition, important background material on goal setting, the nature of information, related aspects of human nature and key perspectives of time and space are discussed. Applying the process to forming rational opinions in such areas as religion and politics is also addressed. The semi-quantitative process that the author calls "Probabilistic Rationalism" is derived from more formal decision theory methodology routinely used by management in making crucial business decisions, especially in situation possessing a significant degree of uncertainty. Applying this useful technique to situations frequently encountered in every-day life can help achieve a "gold medal" in that most important game, "the game of life."