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Williams Hematology, 9E

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Notă GoodReads:
en Limba Engleză Carte Hardback – 16 Jan 2016

The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases
Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields.
The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis.
Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.

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Specificații

ISBN-13: 9780071833004
ISBN-10: 0071833005
Pagini: 2528
Dimensiuni: 221 x 282 x 74 mm
Greutate: 4.45 kg
Ediția: 9
Editura: McGraw Hill Education
Colecția McGraw-Hill Education / Medical
Locul publicării: United States

Cuprins

1
Initial approach to the patient: History and physical examination
2
Examination of blood cells
3
Examination of the marrow
4
Consultative Hematology
5
Structure of the marrow and hematopoietic microenvironment
6
The organization and structure of lymphoid tissues
7
Hematology of the fetus and newborn
8
Hematology during pregnancy
9
Hematology in older persons
10
Genetic principles
11
Genomics
12
Epigenetics
13
Cytogenetic and Genetic Abnormalities
14
Metabolism of Hematological Neoplastic Cells
15
Apoptosis and Autophagy
16
Cell cycle regulation and hematological disorders
17
Signal transduction pathways
18
Hematopoietic stem cells, progenitors, and cytokines
19
The inflammatory response
20
Innate immunity
21
Adaptive immunity
22
Pharmacology and toxicity of antineoplastic drugs
23
Hematopoietic stem cell transplantation
24
Treatment of infections in the immunocompromised host

25
Antithrombotic therapy
26
Immune cell therapy
27
Vaccine therapy

28
Therapeutic apheresis: indications, efficacy, and complications

29
Gene transfer for therapy

30
Regenerative Medicine: Multipotential cell therapy for tissue replacement

31
Structure and Composition of the Erythrocyte
Absorb former 30 Composition of Erythrocyte.
32
Erythropoiesis

33
Erythrocytes turnover

34
Clinical manifestations and classification of erythrocyte disorders
35
Aplastic anemia

36
Pure red cell aplasia
37
Anemia of chronic disease
38
Erythropoietic effects of endocrine disorders

39
The congenital dyserythropoietic anemias
40
Paroxysmal nocturnal hemoglobinuria
41
Folate, cobalamin and megaloblastic anemias
42
Iron Metabolism

43
Iron deficiency and overload
44
Anemia resulting from other nutritional deficiencies


Notă biografică

Kenneth Kaushansky, MD (Stony Brook, NY) is Senior Vice President, Health Sciences and Dean of the School of Medicine, Stony Brook University.

Marshall A. Lichtman, MD (Rochester, NY) is Professor of Medicine and of Biochemistry and Biophysics, University of Rochester Medical Center.

Josef T. Prchal, MD (Salt Lake City, UT, and Prague, Czech Republic) is Professor of Medicine, Pathology, and Genetics, Hematology Division of the University of Utah, and Department of Pathophysiology, First Faculty of Medicine, Charles University in Prague.

Marcel M. Levi, MD, PhD (Amsterdam, The Netherlands) is Chairman of the Department of Medicine at the Academic Medical Center, University of Amsterdam.

Oliver W. Press, MD, PhD (Seattle, WA) is Member and Penny E. Petersen Endowed Chair of Lymphoma Research, Fred Hutchinson Cancer Research Center, Professor of Medicine at the University of Washington.

Linda J. Burns, MD (Minneapolis, MN) is Vice President and Medical Director, Health Services Research at National Marrow Donor Program/Be The Match.

Michael A. Caligiuri, MD (Columbus, OH) is Director, Comprehensive Cancer Center, CEO, James Cancer Hospital & Solove Research Institute, JL Marakas Nationwide Insurance Enterprise Foundation Chair of Cancer Research, The Ohio State University.