Lahore city is very highly polluted. The major causes of which are alarmingly increasing number of motor vehicles and a large number of industries. The research highlights the spatio-temporal patterns of sample pollutants including Sulfur dioxide, Oxides of Nitrogen, Carbon monoxide Ozone, and Particulate matter. The concentrations of these pollutants have been monitored at ten sample sites in the city. The effects of increasing air pollution on population of study area have been studied using questionnaire techniques. The results indicate that the levels of all these pollutants were very high and people in study area were suffering from various diseases such as eye irritation, headache and bronchial disorders.