Systemic Treatment of Prostate Cancer: Oxford Oncology Library
Editat de Alan Horwichen Limba Engleză Paperback – 11 feb 2010
sequential therapeutic interventions. For patients with high risk local disease or with metastases, endocrine therapy is central to management. Hormone ablation has long been the mainstay of endocrine therapy in this group of patients, though anti-androgens, oestrogens, and corticosteroids can also
cause remissions. In recent years effective and well-tolerated chemotherapy regimens have been developed and evaluated. Docetaxel has an established role, and a range of biologically-targeted agents are in development. The dominant pattern of metastatic spread is to the axial skeleton and most symptomatic care is directed to palliation of bone pain. The role of bisphosphonates remains controversial, but bone-directed isotopes such as Strontium-89 are effective. Part of the Oxford Oncology Library, this pocketbook summarizes the up-to-date information on the use of systemic therapies in the management of prostate cancer (early stage, metastatic disease, and treatment of biochemical recurrence). With contributions from leading oncologists from both Europe
and the USA, the book provides a practical guide to the range of endocrine and cytotoxic therapies currently available to clinicians, as well as to other palliative anticancer strategies, and will be valuable to all health professionals involved in the management of patients with prostate cancer.
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Specificații
ISBN-13: 9780199561421
ISBN-10: 0199561427
Pagini: 104
Ilustrații: 2 line drawings
Dimensiuni: 100 x 180 x 5 mm
Greutate: 0.09 kg
Editura: Oxford University Press
Colecția OUP Oxford
Seria Oxford Oncology Library
Locul publicării:Oxford, United Kingdom
ISBN-10: 0199561427
Pagini: 104
Ilustrații: 2 line drawings
Dimensiuni: 100 x 180 x 5 mm
Greutate: 0.09 kg
Editura: Oxford University Press
Colecția OUP Oxford
Seria Oxford Oncology Library
Locul publicării:Oxford, United Kingdom
Descriere
Prostate
cancer
is
one
of
the
commonest
cancers
in
men
in
the
western
world,
and
the
prevalence
is
rising
currently
due
to
improvements
in
screening
and
treatment.
Serum
PSA
represents
a
useful
marker
of
disease.
It
has
frequently
a
long
natural
history,
creating
the
opportunities
for
multiple
sequential
therapeutic
interventions.
For
patients
with
high
risk
local
disease
or
with
metastases,
endocrine
therapy
is
central
to
management.
Hormone
ablation
has
long
beenthe
mainstay
of
endocrine
therapy
in
this
group
of
patients,
though
anti-androgens,
oestrogens
and
corticosteroids
can
also
cause
remissions.
In
recent
years
effective
and
well-tolerated
chemotherapy
regimens
have
been
developed
and
evaluated.
Docetaxel
has
an
established
role,
and
a
range
ofbiologically-targeted
agents
are
in
development.The
dominant
pattern
of
metastatic
spread
is
to
the
axial
skeleton
and
most
symptomatic
care
is
directed
to
palliation
of
bone
pain.
The
role
of
bisphosphonates
remains
controversial,
but
bone-directed
isotopes
such
as
Strontium-89
are
effective.Part
of
the
Oxford
Oncology
Library,
this
pocketbook
summarises
the
up-to-date
information
on
the
use
of
systemic
therapies
in
the
management
of
prostate
cancer
(early
stage,
metastatic
disease,
and
treatment
of
"biochemical"
recurrence).
With
contributions
from
leading
oncologists
from
both
Europe
and
the
USA,
the
book
provides
a
practical
guide
to
the
range
of
endocrine
and
cytotoxic
therapies
currently
available
to
clinicians,
as
well
as
to
other
palliative
anticancer
strategies,
and
will
bevaluable
to
all
health
professionals
involved
in
the
management
of
patients
with
prostate
cancer.
Notă biografică
Alan
Horwich
is
Professor
of
Oncology
at
the
Royal
Marsden
Hospital
and
Institute
of
Cancer
Research,
Sutton,
UK.