In this issue of Radiologic Clinics, guest editors Drs. Mylene T. Truong and Girish S. Shroff bring their considerable expertise to the topic of Pearls and Pitfalls in Thoracic Disease Imaging. Top experts provide insights on interstitial lung disease, lung cancer, subsolid lung nodules, mediastinal masses, and the aorta. Additional articles cover LungRADS, CAD-RADS, PET/CT pitfalls, and imaging of post-surgical complications of lung cancer.