Men's Reproductive and Sexual Health throughout the Lifespan: An Integrated Approach to Fertility, Sexual Function, and VitalityEditat de Douglas T. Carrell, James M. Hotaling, Alexander W. Pastuszak
en Limba Engleză Hardback – 30 sep 2023
Section I. An Introduction to Men's Health Care: 1. How has men's health changed over the past two decades?; 2. The business landscape of men's health; 3. Urologic men's health, the internet, and social media; Section II. The Biology of Male Reproduction and Infertility: 4. Current understanding of the physiology and histology of human spermatogenesis; 5. Male reproductive endocrinology; 6. Sperm chromatin packaging and the toroid linker model; 7. Ejaculation and sperm transport: physiology and clinical concerns; 8. Genetic aspects of male infertility; 9. The mechanistic and predictive utility of sperm epigenetics; 10. Aging and environmental interactions with the sperm epigenome; 11. The effects of aging on male fertility and the health of offspring; Section III. Clinical Evaluation and Treatment of Male Infertility: 12. Office evaluation of the infertile male; 13. Medical management of male fertility; 14. Surgical management of male infertility; 15. Varicocele repair in the era of ICSI; 16. Implementing genetic testing of male infertility in the clinic; 17. Andrological care of the patient with spinal cord injury; 18. Clinical fertility preservation decision making for prepubertal and postpubertal individuals with male gametes; 19. Mental health considerations in the infertile male and couple; Section IV. Laboratory Evaluation and Treatment of Male Infertility: 20. The modern semen analysis: theory and techniques of ejaculate examination; 21. The future of computer-assisted semen analysis in the evaluation of male infertility; 22. Reactive oxygen species and sperm DNA damage; 23. Clinical value of sperm DNA fragmentation tests; 24. The current use of sperm function assays; 25. Sperm selection in the laboratory; 26. Methods to select ejaculated, epididymal, and testicular spermatozoa for assisted conception; 27. Optimal sperm selection in the ICSI era; 28. Microfluidics for sperm sample preparation and sperm identification; 29. Practical concerns for patient semen banking; 30. The potential future applications of in vitro spermatogenesis in the clinical laboratory; 31. Spermatogonial stem cell culture and future of germline gene editing; Section V. Medical and Surgical Management of Issues of Male Health: 32. Hypogonadism in the male: evaluation and treatment; 33. Selective androgen receptor modulators (SARMs) in the treatment of hypogonadism and men's health; 34. Male fertility and testosterone therapy; 35. Sleep and men's health; 36. Molecular biology and physiology of erectile function and dysfunction; 37. Evaluation of the male with erectile dysfunction; 38. Lifestyle modifications for erectile dysfunction; 39. Medical and surgical management of erectile dysfunction; 40. Surgical management of Peyronie's disease; 41. Medical management of BPH; 42. Chronic orchialgia.
Practical and integrated approach to male reproductive and sexual health and how to manage patients with infertility and sexual dysfunction.