The book addresses the need to investigate new approaches to lower energy requirement in multiple application areas and serves as a guide into emerging circuit technologies. It explores revolutionary device concepts, sensors, and associated circuits and architectures that will greatly extend the practical engineering limits of energy-efficient computation. The book responds to the need to develop disruptive new system architecutres, circuit microarchitectures, and attendant device and interconnect technology aimed at achieving the highest level of computational energy efficiency for general purpose computing systems.