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Karyogamic Theory of Cancer Cell Formation from the View of the XXI Century

De (autor) ,
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en Limba Engleză Carte Hardback – July 2010
In this book mechanisms of development of cancer cells through hybridisation of somatic cells are discussed which leads to the karyogamy, hybridisation, "two synkaryon" theory of carcinogenesis. In the case of perforations of plasmatic membranes when cells first approach each other, they then interact and in the case of perforations homology can produce double nuclear aggregation (dikaryon). After fusion of two nuclei inside the dikaryon a single nuclear hybrid cell, i.e. precancerous synkaryon, can be produced. Mechanism of cancerous transformation of precancerous cell into the final cancer cell is based on several molecular-genetic transformations. Cancer progression can be associated with the fusion of a cancer cell with the normal somatic cell. In the plasmatic membrane of the cancerous sincaryon an antigenic profile of the normal somatic cell is incorporated which preserves development of specific immune response. The book is dedicated to advanced academic level specialists.
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Specificații

ISBN-13: 9781608763863
ISBN-10: 1608763862
Pagini: 179
Dimensiuni: 184 x 260 x 16 mm
Greutate: 0.50 kg
Ediția: New.
Editura: Nova Science Publishers Inc

Cuprins

History of the problem; Hybrid cells receiving methods & mechanism of cells fusion; Geno- & phenotypical characteristics of hybrid cells; Utilisation of somatic hybridisation in biology & medicine; Etiology & pathogenesis of cancer; Factors, inducing the malignant process; Karyogamic theory of carcinogenesis (theory of "two synkaryons"); Experimental & clinical confirmations of karyogamic theory; Explanation of different complicated aspects of the experimental & clinical oncology from the standpoint of karyogamic theory; Etiology & pathogenesis of AIDS; A possible common etiology & pathogenesis of cancer & AIDS; A possible reason of interrelation of some malignant tumours & AIDS; A paradoxical idea of cancer's resolution; Summary; Conclusion; Bibliography; Index.