Fetal and Neonatal Physiology, 2-Volume Set: Polin Fiziologie fetală și neonatală

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en Limba Engleză Carte Hardback – 12 Jul 2016

Fetal & Neonatal Physiology provides neonatologist fellows and physicians with the essential information they need to effectively diagnose, treat, and manage sick and premature infants. Fully comprehensive, this 2-volume resource continues to serve as an excellent reference tool, focusing on the basic science needed for exam preparation and the key information required for full-time practice.
The 5th edition is the most substantially updated and revised edition ever. In the 5 years since the last edition published, there have been thousands of publications on various aspects of development of health and disease; Fetal and Neonatal Physiology synthesizes this knowledge into definitive guidance for today's busy practitioner.

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ISBN-13: 9780323352147
ISBN-10: 0323352146
Pagini: 1928
Ilustrații: Approx. 1070 illustrations (900 in full color)
Dimensiuni: 222 x 281 x 110 mm
Greutate: 5.56 kg
Ediția: 5
Editura: Elsevier


Section I - Genetics and Embryology

  1. Basic Genetic Principles
  2. Prenatal Diagnosis
  3. Basic Embryology
  4. Regulation of Embryogenesis
  5. The Extracellular Matrix in Development
  6. Stem Cell Biology
  7. Apoptotic Cell Death
  8. Angiogenesis
  9. Epigenetics Section II - Placenta and Intrauterine Environment
  10. Placental Development
  11. Regulation of the Placental Circulation
  12. Mechanisms of Transfer Across the Human Placenta
  13. Endocrine and Paracrine Function of the Human Placenta
  14. Fetal and Maternal Responses to Intrauterine Infection
  15. Fetal Origins of Adult Disease: A Classic Hypothesis with New Relevance
  16. Physiologic Effects of Multiple Pregnancy on Mother and Fetus
  17. Placental function in intrauterine growth restriction Section III - Developmental Pharmacology and Pharmacokinetics
  18. Basic Pharmacologic Principles
  19. Principles of Pharmacokinetics
  20. Physicochemical and Structural Properties Regulating Placental Drug Transfer
  21. Pharmacogenetics
  22. Drug Distribution in Fetal Life
  23. Drug Transfer During Breastfeeding Section IV - Intrauterine and Postnatal Growth
  24. Circulatory and Metabolic Changes Accompanying Fetal Growth Restriction
  25. Endocrine Factors Affecting Neonatal Growth
  26. Human Milk Composition and Function in the Infant
  27. Physiology of Lactation Section V - Perinatal Iron, Mineral, and Vitamin Metabolism
  28. Fetal and Neonatal Iron Metabolism
  29. Neonatal Calcium, Phosphorus, and Magnesium Homeostasis
  30. Zinc in the Fetus and Neonate
  31. Vitamin A Metabolism in the Fetus and Neonate
  32. Vitamin E Metabolism in the Fetus and Newborn Infant
  33. Vitamin K Metabolism in the Fetus and Neonate Section VI - Lipid Metabolism
  34. Maternal-Fetal Transfer of Lipid Metabolites
  35. Brown Adipose Tissue: Development and Function
  36. Lipids as an Energy Source for the Premature and Full-Term Neonate
  37. Ketone Body Production and Metabolism in the Fetus and Neonate
  38. Long-Chain Fatty Acids in the Developing Retina and Brain Section VII - Carbohydrate Metabolism
  39. Metabolism of Glucose and Methods of Investigation in the Fetus and Newborn
  40. Carbohydrate Metabolism During Pregnancy
  41. Oxygen Consumption and General Carbohydrate Metabolism of the Fetus
  42. Role of Glucoregulatory Hormones in Hepatic Glucose Metabolism During the Perinatal Period
  43. Cell Glucose Transport and Glucose Handling During Fetal and Neonatal Development Section VIII - Protein Metabolism
  44. General Concepts of Protein Metabolism
  45. Fetal Requirements and Placental Transfer of Nitrogenous Compounds Section IX - Thermoregulation
  46. Temperature Control in Newborn Infants
  47. Responses of the Fetus and Neonate to Hypothermia Section X - Skin
  48. Structure and Development of Skin and Cutaneous Appendages
  49. Physiologic Development of the Skin Section XI - Fetal and Neonatal Cardiovascular Physiology
  50. Cardiovascular Development
  51. Developmental Electrophysiology in the Fetus and Neonate
  52. Developmental Biology of the Pulmonary Vasculature
  53. Development of the Gastrointestinal Circulation in the Fetus and Newborn
  54. Physiology of Congenital Heart Disease in the Neonate
  55. Neural Regulation of Blood Pressure During Fetal and Newborn Life
  56. Developmental Effects on Fetal Circulation
  57. Mechanisms Regulating Closure of the Ductus Arteriosus
  58. Umbilical Circulation
  59. Fetal and Placental Circulation During Labor
  60. Physiology of Resuscitation Section XII - The Lung
  61. Normal and Abnormal Structural Development of the Lung
  62. Regulation of Alveolarization
  63. Physiologic Mechanisms of Normal and Altered Lung Growth Before and After Birth
  64. Molecular Mechanisms of Lung Development and Lung Branching Morphogenesis
  65. Regulation of Liquid Secretion and Absorption by the Fetal and Neonatal Lung
  66. Upper Airway Structure: Function, Regulation, and Development
  67. Regulation of Lower Airway Function
  68. Functional Development of Respiratory Muscles
  69. Mechanics of Breathing
  70. Pulmonary Gas Exchange in the Developing Lung
  71. Oxygen Transport and Delivery
  72. Control of Breathing in Fetal Life and Onset and Control of Breathing in the Neonate
  73. Basic Mechanisms of Oxygen Sensing and Response to Hypoxia
  74. Evaluation of Pulmonary Function in the Neonate
  75. Mechanisms of Neonatal Lung Injury
  76. Impaired Lung Growth After Injury in Premature Lung
  77. Antenatal Factors That Influence Postnatal Lung Development and Injury
  78. Regulation of Pulmonary Circulation Section XIII - Surfactant
  79. Historical Perspective
  80. Composition of Pulmonary Surfactant Lipids and Proteins
  81. Structure And Development of Alveolar Epithelial Cells
  82. Regulation of Surfactant-Associated Phospholipid Synthesis and Secretion
  83. Hormonal Therapy for Prevention of Respiratory Distress Syndrome
  84. Surfactant Treatment
  85. Genetics and Physiology of Surfactant Protein Deficiencies Section XIV - Physiology of Gastrointestinal Tract in the Fetus and Neonate
  86. Trophic Factors and Regulation of Gastrointestinal Tract and Liver Development
  87. Organogenesis of the Gastrointestinal Tract
  88. Development of the Enteric Nervous System
  89. Development of Gastric Secretory Function
  90. Development of Gastrointestinal Motility
  91. Development of the Exocrine Pancreas
  92. Digestive-Absorption Functions in Fetuses, Infants, and Children
  93. Development of the Intestinal Microbiome Section XV - Liver and Bilirubin Metabolism
  94. Organogenesis and Histologic Development of the Liver
  95. Bile Acid Metabolism During Development
  96. Neonatal Bilirubin Metabolism
  97. Hereditary Contribution to Neonatal Hyperbilirubinemia
  98. Mechanisms of Action of Phototherapy for Neonatal Hyperbilirubinemia Section XVI - The Kidney
  99. Embryogenesis and Anatomic Development of the Kidney
  100. Functional Development of the Kidney in Utero
  101. Development and Regulation of Renal Blood flow in the Neonate
  102. Development of the Renin-Angiotensin System
  103. Postnatal Development of Glomerular Filtration Rate in Neonates
  104. Renal Transport of Sodium During Early Development
  105. Potassium Homeostasis in the Fetus and Neonate
  106. Role of the Kidney in Calcium and Phosphorus Homeostasis
  107. Transport of Amino Acids in the Fetus and Neonate
  108. Developmental Aspects of Organic Acid Transport
  109. Concentration and Dilution of the Urine
  110. Development of Acidification Mechanisms in the Fetus and Neonate
  111. Response to Nephron Loss in Early Development Section XVII - Fluid and Electrolyte Metabolism
  112. Fluid Distribution in the Fetus and Neonate
  113. Regulation of Acid-Base Balance in the Fetus and Neonate Section XVIII - Developmental Hematopoiesis
  114. Developmental Biology of Stem Cells: From the Embryo to the Adult
  115. Developmental Granulocytopoiesis
  116. Developmental Erythropoiesis
  117. Developmental Megakaryocytopoiesis Section XIX - Hemostasis
  118. Developmental Hemostasis
  119. Platelet-Vessel Wall Interactions Section XX - Developmental Immunobiology
  120. Host Defense Mechanisms Against Bacteria
  121. Host-Fungi Interactions Relevant to the Newborn Infant
  122. Host Defense Mechanisms Against Viruses
  123. T-Cell Development
  124. B-Cell Development
  125. Mononuclear Phagocyte System
  126. Normal and Abnormal Neutrophil Physiology in the Newborn
  127. The Complement System of the Fetus and Newborn
  128. Cytokines and Inflammatory Response in the Fetus and Neonate
  129. Immunology of Human Milk and Host Immunity
  130. Neonatal Pulmonary Host Defense Section XXI - Neurology
  131. Development of the Nervous System
  132. Development of the Blood-Brain Barrier
  133. Trophic Factor and Nutritional and Hormonal Regulation of Brain Development
  134. Intraventricular Hemorrhage in the Neonate
  135. Cerebellar Development - an Impact of Preterm Birth and Co-Morbidities
  136. Electroencephalography in the Premature and Full-Term Infant
  137. Developmental Aspects of Pain Section XXII - Special Sensory Systems in the Fetus and Neonate
  138. Early Development of the Human Auditory System
  139. Development of Taste and Smell in the Neonate Section XXIII - Orthopedics
  140. The Growth Plate: Embryologic Origin, Structure, and Function
  141. Ontogenesis of Striated Muscle Section XXIV - Endocrine Function
  142. Hypothalamus: Neuroendometabolic Center
  143. Growth Factor Regulation of Fetal Growth
  144. Growth Hormone in the Fetus and Newborn
  145. Luteinizing Hormone and Follicle-Stimulating Hormone Secretion in the Fetus and Newborn
  146. Development of the Corticotropin-Releasing Hormone-Corticotropin System in the Mammalian Fetus
  147. Fetal and Neonatal Adrenocortical Physiology
  148. Fetal and Neonatal Thyroid Physiology Section XXV - Ovary and Testis
  149. Genetics of Sex Determination and Differentiation
  150. Differentiation of the Ovary
  151. Testicular Development and Descent Section XXVI - Pathophysiology of Neonatal Diseases
  152. Pathophysiology of Neonatal sepsis
  153. Pathophysiology of Hypoglycemia in the Neonate
  154. Pathophysiology of Cardiomyopathies
  155. Pathophysiology of Persistent pulmonary hypertension of the newborn
  156. Pathophysiology of Shock in the Fetus and Neonate
  157. Pathophysiology of Apnea of Prematurity
  158. Pathophysiology of Respiratory Distress Syndrome
  159. Pathophysiology of Meconium Aspiration Syndrome
  160. Pathophysiology of Bronchopulmonary Dysplasia
  161. Pathophysiology of Ventilator Dependent Infants
  162. Pathophysiology of Gastroesophageal Reflux
  163. Pathophysiology of Neonatal Necrotizing Enterocolitis
  164. Pathophysiology of Kernicterus
  165. Pathophysiology of neonatal acute kidney injury
  166. Pathophysiology of Edema
  167. Pathophysiology of Retinopathy of Prematurity
  168. Pathophysiology of Hypoxic-ischemic Brain Injury
  169. Pathophysiology of Neonatal White Matter Injury
  170. Pathophysiology of Meningitis
  171. Pathophysiology of Neural Tube Defects
  172. Pathophysiology of Preeclampsia
  173. Pathophysiology of Preterm Birth
  174. Pathophysiology of Chorioamnionitis