Cell Biology

Thomas D. Pollard

William C. Earnshaw

Jennifer Lippincott-Schwartz

Graham Johnson

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The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today's students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time.

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Section 1: Introduction to Cell Biology
1 Introduction to Cells
2 Evolution of Life on Earth
Section 2: Chemical and Physical Background
3 Molecules: Structures and Dynamics
4 Biophysical Principles
5 Macromolecular Assembly
6 Research Strategies
Section 3: Chromatin, Chromosomes, and the Cell Nucleus
7 Chromosome Organization
8 DNA Packaging in Chromatin and Chromosomes
9 Nuclear Structure and Dynamics
Section 4: Central Dogma: From Gene to Protein
10 Gene Expression
11 Eukaryotic RNA Processing
12 Protein Synthesis and Folding
Section 5: Membrane Structure and Function
13 Membrane Structure and Dynamics
14 Membrane Pumps
15 Membrane Carriers
16 Membrane Channels
17 Membrane Physiology
Section 6: Cellular Organelles and Membrane Trafficking
18 Posttranslational Targeting of Proteins
19 Mitochondria, Chloroplasts, Peroxisomes
20 Endoplasmic Reticulum
21 Secretory Membrane System and Golgi Apparatus
22 Endocytosis and the Endosomal Membrane
23 Processing and Degradation of Cellular Components
Section 7: Signaling Mechanisms
24 Plasma Membrane Receptors
25 Protein Hardware for Signaling
26 Second Messengers
27 Integration of Signals
Section 8: Cellular Adhesion and the Extracellular Matrix
28 Cells of the Extracellular Matrix and Immune System
29 Extracellular Matrix Molecules
30 Cellular Adhesion
31 Intercellular Junctions
32 Connective Tissues
Section 9: Cytoskeleton and Cellular Motility
33 Actin and Actin-Binding Proteins
34 Microtubules and Centrosomes
35 Intermediate Filaments
36 Motor Proteins
37 Intracellular Motility
38 Cellular Motility
39 Muscles
Section 10: Cell Cycle
40 Introduction to the Cell Cycle
41 G1 Phase and Regulation of Cell Proliferation
42 S Phase and DNA Replication
43 G2 Phase and Control of Entry into Mitosis
44 Mitosis and Cytokinesis
45 Meiosis
46 Programmed Cell Death
Glossary
Appendix

Notă biografică

Thomas Dean Pollard is a prominent educator, cell biologist and biophysicist whose research focuses on understanding cell motility through the study of actin filaments and myosin motors. He is Sterling Professor of Molecular, Cellular & Developmental Biology and a Professor of Cell Biology and Molecular Biophysics & Biochemistry at Yale University. He was Dean of Yale's Graduate School of Arts and Sciences from 2010 to 2014, and President of the Salk Institute for Biological Studies from 1996 to 2001. Pollard is very active in promoting scientific education and research primarily through two major societies, both of which he is a past President: the American Society for Cell Biology and the Biophysical Society

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