Autophagy Processes and Mechanisms

Autor Rohan Dhiman, Sujit K. Bhutia
en Limba Engleză Paperback – 15 sep 2023
Autophagy Processes and Mechanisms details the process of autophagy and its significance in diseases and aging. It provides insights into autophagy mechanisms and processes to broaden our understanding. By collecting recent progress on several aspects of the autophagy process, it provides a more integrative perspective and serves as a resource that can influence future research initiatives in the field. This new book is appropriate for basic and applied researchers in cell biology, biologists and those working in the pharmaceutical sciences.

  • Includes cutting-edge knowledge on autophagy processes as well as methodologies of research
  • Integrates knowledge from the perspectives of basic biological science, bioinformatics, clinical research and the pharmaceutical sciences
  • Provides an educational resource for students and investigators with an interest in autophagy, but who are not currently working in the field
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ISBN-13: 9780323901420
ISBN-10: 0323901425
Pagini: 242
Dimensiuni: 152 x 229 mm


1. mTOR signalling and autophagy regulation
2. AMPK signalling in autophagy induction
3. ATG1/ULK1 complex in autophagy
4. Beclin-1-associated complex in autophagy and regulation  
5. Autophagy conjugation system in autophagy
6. ATG8 family protein, cargo selection and autophagy
7. Mechanism of autophasosome and lysosomal fusion in autophagy
8. Lysosome in autophagy induction and cellular homeostasis
9. Autophagic lysosmal reformation: the beginning from end
10. Lipid in membrane formation for autophagosome and autophagy induction
11. Implication of autophagy in health, diseases and aging
12. Detection and experimental analysis of autophagy and processes for future research applications

Notă biografică

Rohan Dhiman is Associate Professor in the Department of Life Science at Rourkela, Odisha, India. He completed his Ph.D. at Institute of Microbial Technology, Chandigarh before moving to University of Texas Health Science Centre at Tyler for post-doctorate training. After four years there with virulent mycobacteria to study the role of NK cells, regulatory T-cells and monocyte heterogeneity in tuberculosis, he returned to India and joined as a Research Scientist in Translational Health Science and Technology Institute where he started studying different facets of pathways related to autophagy and post-translational modification regulated by mycobacterium in infected macrophages. After joining in current institute in 2014, he started his independent lab and currently focusing on screening some libraries w.r.t. autophagy induction ability of the molecules and Calcimycin is one of the compounds that his lab found through this approach. He has published 35 papers till now and co-authored different book chapters.