In this issue of Gastrointestinal Endoscopy Clinics of North America, guest editors Drs. Violeta Popov and Shelby Sullivan bring their considerable expertise to the topic of Advances in Bariatric and Metabolic Endoscopy. Minimally invasive metabolic and bariatric endoscopic therapies can bridge the gap between surgical interventions and medical therapy, and recent advances have facilitated personalized and patient-targeted treatment options for specific disease states. In addition, these techniques can target different parts of the GI tract that may be responsible for the pathophysiology of obesity and metabolic syndromes. This issue provides state-of-the-art clinical reviews on the technical aspects of these procedures as well as patient management.